Hi Neil

I had a recent issue where I could only open Outlook in Safe mode.  Like you I did all the usual things, Repair, Reinstall etc.

It turned out to be a corrupted preferences file (C:\Documents and Settings\profile_name\Application Data\Microsoft\Outlook\outcmd.dat)

I deleted it and Outlook re-created a new one the next time it opened.  This fixed my problem.

 IHTH

 Regards  Bruce Richardson

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Have a weird one here.

XP Pro

Office Pro 2007

Outlook would get an error opening and would only open in safe mode.

Email account was an IMAP account

To get outlook working I have done the following:

Uninstalled Office rebooted and reinstalled office – made no difference

Uninstalled Office rebooted then followed Microsoft’s method for manually uninstalling all references to office including the registry – rebooted and reinstalled office – made no difference.

Also removed, not just disabled, all addins – no good.

I have even started outlook without email support.

It does not matter what I try Outlook encounters a problem and closes.

It will only open in safe mode.

Have seen this problem many times but the one that usually fixes it is the deletion of a registry key for the “Protected Storage System Provider” this link from Microsoft gives you three steps to try to fix it. http://support.microsoft.com/kb/290684